For very dry skin, skin with wrinkles that lacks elasticity. Modifying and brightening. Can be used during the day, but should be used at night to improve elasticity and fight wrinkles.
Use Biologique Recherche Serum Amniotique E or Serum Colostrum Pur underneath, and either Serum Grand Millesime or Le Grand Serum with both Fluide VIP O2 and Yall O2 together.
One of the best creams offered by Biologique Recherche.
 Helps to reduce the appearance of fine lines and wrinkles
 Encourages the optimal synthesis of supportive fibbers.
 Helps to prevent the visible signs of aging
 Helps to improve skin elasticity
 Hydrates and brightens the complexion Soothes your skin within 2 weeks.
 The appearance of existing lines is visibly reduced :
- 40% on crow’s feet
- 20% on forehead lines
- 22% on smille lines
 Your skin is soften, radiant and visibly younger.
 A concentrate of high grade ingredients.

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Apply a hazelnut-sized amount of Crème Biofixine over all the face, neck and cleavage after previously using the recommended Lotion P50.


Anti-wrinkle agents: Green Anise Extract, Walnut Extract.

Antioxidant agent: Edelweiss Extract.

Oxygenating and regenerating agent: Specific BR Oxygenating Complex.

Moisturizing agent: Grape Seed Oil.